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Hypoxia-induced stabilization of HIF1a leads to up-regulation of CXCL12, which in turn mediates recruitment of CXCR4-expressing endothelial progenitor cells from the bone marrow, thereby contributing to vasculogenesis [207]

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Amyloidosis associated with dialysis occurs when blood proteins are deposited on joints and tendons, resulting in discomfort, stiffness, and fluid buildup in the joints