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To our knowledge this is the first study to reveal disruption of the Nrf2 pathway as a mechanism underlying redox disturbances and neutrophil hyperactivity/hyper-reactivity in periodontitis

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Glutatyonun serbest radikalleri toplayarak karaciere gtrdn syledik ve sonrasnda ise kendisini tekrar yenilediini vcudumuzda ideal artlarda %10 orannda inaktif glutatyon, %90 orannda ise aktif glutatyon bulunmaktadr

Moreover, transmission electron microscopy revealed smaller mitochondria, increased membrane density, and fewer cristae, which indicate the morphological signature of ferroptotic cells (Fig