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Woods KA, Camacho-Hbner C, Savage MO, Clark AJ

senescent cells are still involved in many important physiological processes, such as tumor suppression, embryonic development, wound healing and tissue remodeling

Cracking the Folate Code: How Enzymatic Polymorphisms Shape Health and Neurodevelopment

Once activated by their ligands, they undergo a conformational change, promoting their release from chaperone proteins and facilitating their dimerization and translocation to the nucleus, where they bind to specific regions of DNA called hormone response elements, to recruit co-regulators, chromatin remodelers, and the transcription machinery [for review (63, 64)]