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Results HIF-responsive gene expression shows cell type enrichment in kidney tissue To assess the transcriptional response associated with the change in oxygen availability, we created a curated list of HIF response genes (HRG)

Large-scale human trials are needed first, and those have not been initiated as of 2026

Samples were concentrated to dryness in vacuum before dissolving in 150 L 80% methanol solution, then centrifuged again at 13 500 g and 4C for 10 min, and the supernatant was transferred to a new tube for LC-MS detection

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