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Downregulates pro-inflammatory genes and those promoting fibrosis

That GLP-1part of a class of drugs (called glucagon-like peptides) originally designed to treat diabetes that found huge success in aiding weight lossstarted a biochemical stampede that has impacted the treatment of serious diseases and multiple industries (beauty, sexual wellness, brain health, and fitness, to name a few) and made regular people feel okay about routinely injecting a drug into their bodies

Anal Chim Acta 481, 291300 (2003)

Another study in humans reported a positive correlation between circulating TREM2 concentrations and insulin resistance, although there was no association with body weight 58