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To confirm this, the expression of important proteins involved in redox homeostasis, including the NRF2/KEAP1 complex, SODs, and glutathione peroxidase (GPX) enzymes families in both macrophages and RANKL-stimulated BMMs was analyzed by WB

In vivo antiarthritic efficacy Cellular experiments revealing the anti-inflammatory and pro-biomineralization performances of ZMTP nanosheet encouraged us to further explore its antiarthritic efficacy in vivo

Direct inactivation is done by binding to the active site of enzymes containing copper ion, while indirect inactivation eliminates free radicals and peroxides in antioxidative manners