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doi: 10.1016/j.redox.2024.103413 77

However, the pediatric acute liver failure study group has found that in chronic exposure to APAP (in contrast to a single toxic dose), younger patients (median age, 3.5 years) experienced a greater level of hepatotoxicity comparative to older adolescent patients (median age 15.2 years) who were more likely to experience hepatotoxicity from a single toxic dose (Rumack et al., 1981)

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AD Alzheimer 's Disease the HGF mimics described herein are used to treat dementia, e.g