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In order to test if survival bias was sufficient to explain the MR results estimated from this study, we followed the methodology used by Noyce 35 , which consisted of a series of simulations that were performed to obtain the effect sizes that are expected from the frailty effects alone

Propylene glycol, or PG as it is more commonly known, is still incredibly popular as an e-liquid ingredient today, as it is very safe to inhale and effectively imitates the experience of smoking a tobacco cigarette

Cell Culture and Agents Human bronchial epithelial (HBE) cells were purchased from American Type Culture Collection (ATCC, CRL-2741), and were maintained in RPMI 1640 with 10% FBS, 50 U/mL penicillin, and 50 U/mL streptomycin