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Moreover, numerous phenotypic similarities exist between the manifestations of ESRD and the aging process itself ( In non-uremic mice, the loss of the NF-B subunit 1 initiates a chain reaction of chronic inflammation, which in turn accelerates telomere shortening and results in a progressively aging phenotype (Steyers and Miller, 2014

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In precision medicine, the ability to customize nanoparticle composition, size, surface charge, and functionalization allows individualized treatment strategies that align with patient-specific genetic and metabolic profiles