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Pharmacological Research , 47 , 4952

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So that's where all these direct to health, direct to consumer companies have an opportunity to kind of modulate the way medicine is practiced in the United States

(Native, unmodified recombinant human IGF-1, sold as mecasermin/Increlex, is FDA-approved only for a narrow pediatric growth-failure indication and is chemically distinct from the LR3 analog.) In the US it is manufactured and sold almost exclusively as an unregulated "research chemical" labeled "not for human consumption," a labeling practice peptide vendors use to avoid marketing it as an unapproved drug