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No external funding sources were used for the manuscript preparation

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It has gained attention in wellness and regenerative medicine for its potential role in supporting tissue repair, recovery, and overall healing

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Outside clinical trials, cagrilintide exists primarily in the research chemical space

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These changes suggest that the absence of Nrf2 not only diminishes the hosts antioxidant defenses but also weakens intestinal immune function, impairing its ability to control harmful gut bacteria

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