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Moreover, two main types of receptor-mediated mitophagy pathway have been classified as follows in brief: ubiquitin-independent mitophagy receptors, including BCL2-interacting protein 3 (BNIP3) (Quinsay et al., 2010), BCL2-interacting protein 3 like (NIX/BNIP3L) (Sandoval et al., 2008), FUN14 domain-containing 1 (FUNDC1) (Otsu et al., 2015), autophagy and beclin 1 regulator 1 (AMBRA1) (Strappazzon et al., 2015), FKBP prolyl isomerase 8 (FKBP8) (Wei et al., 2017), and NLR family member X1 (NLRX1) (Zhang et al., 2019)

However, individual absorption varies significantly, and no clinical trials have directly compared the two delivery methods

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This vitamin is important for making red blood cells, nerve function, and DNA