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It was suggested that slow turnover of collagen in tendon allows for non-enzymatic crosslinking to accumulate (Avery and Bailey, 2005

The PL-10 trial (a phase 2 study for inflammatory bowel disease) was listed on registries but full peer-reviewed results were not published

[57] Several serious, even life-threatening diseases cause elevated serum haptocorrin, measured as abnormally high serum vitamin B 12 , while at the same time potentially manifesting as a symptomatic vitamin deficiency because of insufficient vitamin bound to transcobalamin II which transfers the vitamin to cells