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[25] In dogs, it is estimated that 60% of cases are congenital with brachycephalic breeds being the most affected due to the oesophageal hiatus' cross-sectional area being larger than normocephalic and doliocephalic dogs

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Storage guidelines Lyophilized (powder) form: Temperature: Store at -20 degrees Celsius for long-term storage, or 2 to 8 degrees Celsius (refrigerator) for short-term storage up to several months Light: Protect from direct light