A 2023 safety review ( Clinical, Cosmetic and Investigational Dermatology ) analyzed 12 studies (n=512): most common adverse events were transient erythema (4.2%) and pruritus (2.8%)
Worth a look if you travel a lot or just hate pinning
Your provider may review: Sleep history Current sleep schedule Mental health symptoms Stress and burnout Medications and supplements Caffeine, alcohol, or substance use Hormonal or metabolic concerns Pain or inflammation Breathing concerns during sleep Prior sleep treatments Safety considerations If DSIP is not appropriate, your provider can help you explore other options that may better fit your needs
In vitiligo patients, an increase in pro-inflammatory cytokines typical of innate immunity, IL IL-1, IL-1, IL-6, IL-8, IL-12, IL-15, and TNF-, is observed in both serum and skin.2,3 Damage-associated molecular patterns The Koebner phenomenon is considered an initial trigger for vitiligo