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HIGHLIGHTS - HIV Patients With HAND Often Develop Early Neurodegeneration and Iron Dysmetyabolism, Likely Implicating Ferroptosis in this pathology

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Results Dexamethasone exposure reduces late ferroptosis To better understand the effect of dexamethasone on ferroptosis in renal pathophysiology, we first leveraged the human-derived renal tubular cell line CD10-135, which has been demonstrated to recapitulate key features of its origin [14]

The gut is inhabited by approximately 100 trillion of these microorganisms, primarily found in the large intestine with a smaller amount in the final part of the small intestine