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Drug-induced liver injury (DILI) is a leading cause of acute liver failure and can be life-threatening

This example is particularly important because both the agonists are endogenous ligands, indicating that the phenomenon of functional selectivity in desensitization is not simply due to non-physiological receptor conformations induced by synthetic ligands

Magnesium is an important mineral involved in many aspects of health

Lipoyl (octanoyl) transferase 2 catalyzes the transfer of the octanoyl moiety from ACP to a conserved lysine in the H protein of the glycine cleavage complex (see Biological Activities and Figure 3)