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Another PMI study showed that IQOS and CS have minimal impact on the intestinal microbiome in mice after six months of exposure 53

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"As the adult population of China grows and the proportion of male deaths due to smoking increases," they continue, "the annual number of deaths in China that are caused by tobacco will rise from about 1 million in 2010 to 2 million in 2030 and 3 million in 2050, unless there is widespread cessation." Like any major demographic trend, there are a number of forces at work driving the out-of-control smoking