By attaching an acetyl group to the sulfur atom of cysteine within the glutathione tripeptide, SAG resists enzymatic degradation in the gastrointestinal tract, crosses cell membranes intact, and is then hydrolyzed intracellularly by cytoplasmic thioesterases to release free, bioactive GSH directly inside cells
Lipids, 37 (10)
I think I remember needling This was a big thing, because I took that course really early, and I remember talking about with Sue, actually, about what are all the other important safety factors I have to think about before I even suggest this to somebody as an option
It is therefore interesting to note the positive effects of antimicrobials clinically in AD patients, most notably the broad spectrum antibiotics cycloserine, a combination of doxycycline and rifampin, and Helicobacter pylori elimination protocols consisting of omeprazole, clarithromycin and amoxicillin, all of which led to cognitive improvements (Catumbela et al., 2023)
