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Molecules 26 , 1844 (2021)

8.4 Final perspective The convergence of evidence from molecular studies, epidemiological investigations, and intervention trials establishes environmental endocrine disruptors as significant threats to male reproductive health with implications extending far beyond individual exposure events

Chlorpyrifos has also been found to inhibit acetylcholine esterase activity in the brain resulting in interference of neuronal transmission involved in the synthesis and/or release of LH and FSH [101]