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Key residues 38 YGSL 41 , D 68 , R 72 , E 115 and Y 143 are responsible for high affinity substrate binding via salt bridge interaction with the glutamate (E 115 ), hydrogen bonding as well as a cation -interaction involving Y 143

2f) as well as DNA fragmentation in HepG2 cells pretreated with exogenous H 2 O 2 (Fig

Pineal function and circadian biology: Studies in aged animals showing restoration of pineal gland function, increased melatonin production, and normalization of disrupted sleepwake cycles

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