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Cells were fixed and stained with 70% ethanol, 0.4% (w/v) methylene blue and destained with distilled water

The swelled endoplasmic reticulum morphology was observed in the group of free OLE and PEG-T ECM -NS/OLE pretreated with pH 6.8 buffer, confirming ICD was elicited by OLE and PEG-T ECM -NS/OLE (Fig

diagnosed by skin punch biopsy for intraepidermal nerve fiber density Erythromelalgia burning with visible redness and warmth, triggered by heat or exercise, relieved by cold