The structure allows it to act as a signaling molecule that may influence tissue repair, blood vessel formation, and cellular response pathways in preclinical models
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A Phase I trial (NCT02637284) in 42 healthy volunteers was initiated circa 2015 and cancelled in 2016 with no data published
Epitalon Treatment Restrains HG-induced Expression of EMT and fibrosis-related Genes EMT of RPE cells is a crucial process in the development of fibrosis associated with vitreoretinal diseases, including PDR [32]
