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Furthermore, prior to division, Drp1, Mff, and MiD49/51 bind specifically to endoplasmic reticulum-mitochondrial contact sites, where they facilitate mitochondrial membrane remodeling and division (Osellame et al., 2016

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According to meta-analysis data, hypothyroidism occurs in about 3.8% of patients treated with anti-CTLA-4, 3.9% with anti-PD-L1, 7.0% with anti-PD-1, and 13.2% with combination therapy

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