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In both cases, significant effects in the ANOVA were further investigated using simple main-effects pairwise post-hoc tests with idk adjustments for multiple comparisons

Notice that GSH goes up for low estradiol values, reaches a peak and descends for high estradiol values Variation of GSH steady state depending on S In our model, we take the activation of GCL and GPX by estradiol to be 80%, which is a reasonable choice supported by the experimental and clinical data discussed above

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The FDA's Pharmacy Compounding Advisory Committee has meetings scheduled for July 2026 to formally review them for Category 1 placement