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NPT1 ( SLC17A1 ) The SLC17A1 , a membrane protein, is the first member of the SLC17 phosphate transporter family ( SCL17A1 gene encoding NPT1 transports various substrates including UA ( Function of NPT1 ( SLC17A1 ) NPT1, weakly to moderately correlate with altered UA levels, mediates the absorption of UA when the plasma membrane is depolarised by high concentration of exogenous potassium ( -dependent urate transport, has two transportation activities, namely the of Na + /phosphate co-transport