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While its possible to get all the vitamin B12 you need from the foods you eat, in certain cases, a B12 supplement might be useful particularly if youre at greater risk of becoming deficient in B12

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683 Remarkably, the work summarized here on the superoxide dismutases (SODs) and ribonucleotide reductases (RNRs) reveal that cambialism and more generally metalloenzyme paralogs have evolved in enzymes that catalyze more restrictive chemistry, where a change in oxidation state and even access to high-valent intermediates, is involved