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Since the valinomycin synthetase Vlm shows the same genetic architecture as Ces, it is tempting to speculate that the novel mechanism of non-ribosomal peptide assembly proposed in this study is not a specificity of the cereulide synthetase but a more common logic for biosynthesis of ester bond containing NRPS products, thereby contributing to biodiversity of natural depsipeptide products

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Combining them with a peptide that also increases nitric oxide production could theoretically produce excessive vasodilation, leading to dangerous blood pressure drops

However, the enforcement environment has intensified significantly, and researchers should understand the legal landscape for peptides in their jurisdiction before purchasing