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For patients in whom cisplatin cannot be used, carboplatin can be substituted but non-randomised data have shown lower response rates and high rates of haematological toxicity for carboplatin-based combinations, albeit with similar survival figures to patients receiving cisplatin

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Those in the higher income classification (representing individuals with annual incomes at 300 percent of the poverty level or higher and comprising 45 percent of the total sample) were significantly less likely to smoke than those at lower income levels