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The crystal structure of human GGT has recently been solved (West et al., 2013b)

Then, serial dilutions of unlabeled binding partner samples (inhibitor or substrate) were mixed with 0.377 M of dye-labeled TyrBm in 50 mM PBS buffer pH 7.4 and incubated for 5 minutes

In some embodiments, the lipid-based drug delivery formulation or composition comprises a penetration enhancer wherein the penetration enhancer is propylene glycol, either alone or in up to a 1:1 ratio with another enhancer, such as oleic acid or ethanol