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5), and by inference, neurotoxic damage.53 Forgione and colleagues had previously hypothesized that GPX1 deficiency directly induces an increase in vascular oxidative stress, with attendant endothelial dysfunction.54 Glutathione peroxidases, particularly GPx1 have also been implicated in the development and prevention of many common and complex diseases, including cancer and cardiovascular disease (Fig

Additionally, it is also used in the treatment of cyanide poisoning, a condition that can cause rapid breathing, confusion, and seizures

How DNA sensing drives inflammation

Excitotoxicity is a key neurodegenerative mechanism that disrupts neuronal function and survival in CNS disorders [139]