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Lo Bello M, Battistoni A, Mazzetti AP, Board PG, Muramatsu M, Federici G et al

Thus, the mutation has survived in the genome in areas where malaria is (or was) prevalent (Africa, Middle East, India, and Southeast Asia)

The source of sciatic pain is often a deeply seated nerve root near the spinal cord or the piriformis muscle buried under the large gluteus maximus

Megaloblastic anemia due to B12 deficiency is either caused by inadequate intake, in which case oral supplementation is sufficient, or poor absorption potentially due to a reduction in intrinsic factor. Intrinsic factor, which is synthesized by cells in the stomach, is secreted into the gastrointestinal tract to bind dietary B12 and facilitate its absorption (Wickramasinghe 2006)