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This collection of compounds is sometimes referred to as "cobalamins"

Common reasons include: Pernicious anemia , an autoimmune condition affecting intrinsic factor production Gastrointestinal disorders, such as Crohns disease or celiac disease Prolonged use of certain medications, like proton pump inhibitors Knowing these causes helps spot at-risk people

Clinical experience and limited human data suggest daily doses between 200-1000 g, with 500 g representing a commonly reported effective dose, though these figures lack rigorous clinical trial validation

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