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177 Significant heterogeneity exists between multifocal tumor nodules in HCC

Lipocalin 2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is another iron-binding protein that can bind iron-containing complexes (such as catechol-iron complexes) and mediate iron endocytosis through interaction with SLC22A17 (an LCN2 transporter)

DOI: 10.1039/c6ob01815g

Rather than suppressing the entire immune response, these peptides can potentially shift the balance between pro-inflammatory and anti-inflammatory processes, promote regulatory T cell function, and restore tolerance mechanisms that have broken down in lupus