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ChaC-like enzymes act specifically on GSH, GGACT enzymes act on -glutamylamine amino acids, and GGCTs have a broader activity towards -glutamyl amino acids in general
Some practitioners inject near injury site (local administration) versus systemic injection, though evidence for superiority of local injection limited
J Surg Res
Additionally, DA quinones can be oxidized to aminochrome, whose redox-cycling leads to the generation of the superoxide radical and the depletion of cellular nicotinamide adenine dinucleotide phosphate-oxidase (NADPH), which ultimately forms the neuromelanin (Sulzer et al., 2000) known to be accumulated in the SNpc of the human brain (Ohtsuka et al., 2013, 2014
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