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The authors declare that AI-based tools (Doubao) were used to generate the initial draft images for several subpanels in Fig

Many women benefit from complete HRT, including estrogen, progesterone, and testosterone

GSH acts as a scavenger of reactive oxygen species (ROS) such as free radicals, peroxides, lipid peroxides and heavy metals to maintain normal cellular function and resist oxidative stress

(3) Iron homeostasis modulation: iron chelation with deferoxamine (DFO) and inhibition of NCOA4dependent ferritinophagy are illustrated as means to lower the labile iron pool and reduce ironcatalyzed lipid peroxidation