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For instance, MDA reacts with deoxyadenosine and deoxyguanosine in DNA, forming multiple DNA adducts, of which pyrimido[1,2-a]-purin-10(3H)-one (M 1 dG) is a predominant adduct with mutagenic properties [79, 84, 85]

Responding to increasing consumer demand for smarter and safer alternatives to traditional tobacco, manufacturers are further incorporating advanced features such as puff monitoring, child-lock mechanisms, and app integration, ensuring greater convenience, control, and safety for users

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