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Tirzepatide is a dual GIP and GLP-1 receptor agonist, while semaglutide is solely a GLP-1 receptor agonist

In a landmark human trial comparing topical GHK-Cu to vitamin C and retinoic acid (tretinoin), GHK-Cu produced measurable collagen increases in 70% of study volunteers outperforming both comparator treatments (Abdulghani et al., 1998)

Pain 18 , 4253 (2017)

This review also summarizes and highlights current limitations in targeting the Th17/Treg balance for AR treatment and suggests future research directions, aiming to provide new insights and strategies for clinical management (Fig