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This makes vaping gum disease more than just a cosmetic or dental issueit becomes a whole-body health concern

Meanwhile, the cumulative genetic damage significantly raises the risk of lung cancer, which is the leading cause of cancer death worldwide

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In answer to the more direct question of how much nicotine per day is safe, a reasonable starting point might be, "How much nicotine might it take to poison someone?" The ECHA currently gives an "acute toxicity estimate" (ATE) for nicotine via the oral route to be 5 mg/kg bw [7] , meaning 5mg of nicotine for every kilogram of bodyweight of the person consuming the nicotine