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Avoid Thymosin Alpha-1 without consulting your dermatologist, as it modulates immune function in ways that could theoretically interact with immunomodulating drugs

Due to this dysregulated immune response, immunomodulatory drugs are now considered as potential supplementary agents with various immunotherapies including cancer vaccines, immune checkpoint blocking antibodies, adoptive T cell therapy, and dendritic cell (DC) based immunotherapy (Mahoney et al., 2015)

358 As oxidative stress accumulates, DNA damage occurs, promoting the development of senescence in keratinocytes, melanocytes, and dermal fibroblasts