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The symptoms may include: Dry cough Shortness of breath on exertion Wheezing Inflammation Narrowing of the airways Scarring (fibrosis) of the lungs Fatigue CDC: E-Cigarette Use Spikes Among Children The CDC has reported that the number of American children (middle-schoolers in grades 6-8) who have ever tried e-cigarettes doubled from 2011 to 2012, from 3.3% to 6.8%

Sympathetic nervous system activation (fight-or-flight) Nicotine can activate the sympathetic nervous system and increase catecholamine signaling, which may increase resting energy expenditure and activity-related energy expenditure (again described in the review on nicotines effects on energy balance)

For consumers, this effectively means: You cannot legally ship vapes through FedEx or UPS as a private individual

While they remain a risky indulgence health-wise, their appeal goes beyond nicotineits about prestige, taste, and collecting rare treasures