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We have a tantalizing situation: on one hand, a mountain of animal evidence suggests this peptide could be a revolutionary healing therapy

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Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria

Clinical trials demonstrated average weight reductions of 15-21% of body weight over 72 weeks in people with obesity (SURMOUNT-1), while more modest weight loss was observed in type 2 diabetes patients (SURPASS trials)