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it can prevent protein degradation by proteolysis or sulfhydryl overoxidation, plays a key role in cellular signaling and participates in some pathological processes, including atherosclerosis, neurodegenerative disorders, cardiovascular diseases, and several types of cancer [65,68,69,70,71]

This upregulation of VEGF was accompanied by the formation of angiogenic factors, highlighting the intricate interplay between vascular remodeling and neuroinflammation in EAE pathology