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This regulation allows rapid Ca 2 spikes detectable in less than 15 s in Arabidopsis guard cells under osmotic stress (Dong et al.2022), encoding stimulus-specific information

The breadth of gene expression changes observed has been attributed to GHK-Cus role as a signaling molecule that interacts with multiple cellular systems simultaneously

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The gut communicates with the liver via the gutliver axis through the biliary system and the portal vein, transferring gut-derived components or the gut microbes themselves to the liver and initiating the immune response