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Causes of Addiction Genetics, including the impact of ones environment on gene expression, account for about 40% to 60% of a persons risk of addiction.2 Environmental factors that may increase a persons risk of addiction include a chaotic home environment and use, parental drug use and attitude toward drugs, peer influences, community attitudes toward drugs, and poor academic achievement.2 Teenagers and people with mental health disorders are more at risk for drug use and addiction than other populations.2 Drug and alcohol use can be scary