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Amylin analogues have been proven to increase satiety by direct action on amylin receptors and by restoring sensitivity to the hormone leptin

We observed a reduction in insulin, glucose, HOMA-IR, triglyceride, leptin, and several oxidative stress and inflammation biomarker levels and an increase in high-density lipoprotein and adiponectin levels at the end of 4 th week during 4-week intermittent fasting, however, these parameters did not reach statistical significance

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Research has explored its activity in epithelial barrier function, cytokine modulation, and localized inflammatory response mechanisms across multiple tissue types