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The ALDH2*2 allele harbors a Lys(K) residue at position 487 instead of the normal Glu(D) residue

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(1987) J Mol Biol 195 : 701-729 PubMed: 3656429 Search on PubMed DOI: Primary Citation Related Structures: 3GRS PubMed Abstract: The crystal structure of human glutathione reductase has been established at 1.54 A resolution using a restrained least-squares refinement method

Other adverse reactions include: Central Nervous System Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychological dependence, mood changes