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After 48 h, biofilms were washed once with 1 PBS followed by treatment with different concentrations of 0, 5, 10, 25, and 50 M H 2 O 2 (prepared by diluting an aliquot of 30% (v/v) H 2 O 2 in 1 PBS) for 24 h, at 37C and shaking at 150 rpm

Gene regulation by long non-coding RNAs and its biological functions

Integration of ageing biomarkers into BBB research may also provide new insights into therapeutic interventions to restore vascular integrity in ageing and associated neurodegenerative disorders

At present, few studies to date have reported the pharmacological effects of berberine on neurodegenerative diseases, especially in human trials