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Salidroside also increased the ischemic brains BDNF protein and p-TrkB/TrkB ratio

Secretagogues (GHRH and GHRP) stimulate the pituitary gland to produce its own GH, preserving natural pulsatility and hypothalamic feedback mechanisms

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NMDA receptors are an exemplar of this dynamic at work, where the balance between primarily inhibitory effects of NO-mediated NMDA receptor nitration and the bimodal and highly concentration-dependent effects of extracellular polyamines at NMDA receptors put interactive guardrails around the range of permitted NMDA calcium flux (Figure 2