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4 Conclusion In general, the auto-reactive cellular immune responses including osteoclasts, synovial fibroblasts, T cells, B cells, NK cells, macrophages and DCs, play major roles in RA pathogenesis, although soluble inflammatory and rheumatoid factors with inflammatory natures were also involved

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doi: 10.1136/jitc-2022-sitc2022.1129 90 OdehFNsairatHAlshaerWIsmailMAEsawiEQaqishBet al

A prominent example is the federal prosecution of Tailor Made Compounding LLC, which pleaded guilty to the illegal distribution of unapproved peptidesincluding BPC-157resulting in a criminal $1.79 million financial forfeiture